Effect of Human Amnion Epithelial Cells on the Acute Inflammatory Response in Fetal Sheep

Intra-amniotic (IA) lipopolysaccharide (LPS) injection in sheep induces inflammation in the fetus. Human amnion epithelial cells (hAECs) moderate the effect of IA LPS on fetal development, but their influence on the acute inflammatory response to IA LPS is unknown. We aimed to determine the effects...

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Bibliographic Details
Main Authors: Alana Westover, Jacqueline M. Melville, Courtney McDonald, Rebecca Lim, Graham Jenkin, Euan M. Wallace, Timothy J. Moss
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00871/full