Advantages and limitations of different p62-based assays for estimating autophagic activity in Drosophila.

Levels of the selective autophagy substrate p62 have been established in recent years as a specific readout for basal autophagic activity. Here we compared different experimental approaches for using this assay in Drosophila larvae. Similar to the more commonly used western blots, quantifying p62 do...

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Bibliographic Details
Main Authors: Karolina Pircs, Peter Nagy, Agnes Varga, Zsolt Venkei, Balazs Erdi, Krisztina Hegedus, Gabor Juhasz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3432079?pdf=render