Condition-Dependent Coordination and Peroxidase Activity of Hemin-Aβ Complexes

Condition-Dependent Coordination and Peroxidase Activity of Hemin-Aβ Complexes

The peroxidase activity of hemin-peptide complexes remains a potential factor in oxidative damage relevant to neurodegeneration. Here, we present the effect of temperature, ionic strength, and pH relevant to pathophysiological conditions on the dynamic equilibrium between high-spin and low-spin hemi...

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Bibliographic Details
Main Authors: Chiara Bacchella, James T. Brewster, Steffen Bähring, Simone Dell’Acqua, Harrison D. Root, Gregory D. Thiabaud, James F. Reuther, Enrico Monzani, Jonathan L. Sessler, Luigi Casella
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
central nervous system
neurodegeneration
Alzheimer’s disease
hemin
peroxidase
Online Access:https://www.mdpi.com/1420-3049/25/21/5044

Internet

https://www.mdpi.com/1420-3049/25/21/5044

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