Function and mechanism of TREM2 in bacterial infection.

Triggering receptor expressed on myeloid cells 2 (TREM2), which is a lipid sensing and phagocytosis receptor, plays a key role in immunity and inflammation in response to pathogens. Here, we review the function and signaling of TREM2 in microbial binding, engulfment and removal, and describe TREM2-m...

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Bibliographic Details
Main Authors: Zehua Wu, Shiyue Yang, Xiangming Fang, Qiang Shu, Qixing Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011895&type=printable