Smoothened as a new therapeutic target for human osteosarcoma

<p>Abstract</p> <p>Background</p> <p>The Hedgehog signaling pathway functions as an organizer in embryonic development. Recent studies have demonstrated constitutive activation of Hedgehog pathway in various types of malignancies. However, it remains unclear how Hedgeho...

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Bibliographic Details
Main Authors: Nagao Hiroko, Gao Hui, Matsunoshita Yukihiro, Sasaki Hiromi, Setoguchi Takao, Hirotsu Masataka, Kunigou Osamu, Komiya Setsuro
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/5