Maturation of selected human mitochondrial tRNAs requires deadenylation

Maturation of selected human mitochondrial tRNAs requires deadenylation

Human mitochondria contain a genome (mtDNA) that encodes essential subunits of the oxidative phosphorylation system. Expression of mtDNA entails multi-step maturation of precursor RNA. In other systems, the RNA life cycle involves surveillance mechanisms, however, the details of RNA quality control...

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Bibliographic Details
Main Authors: Sarah F Pearce, Joanna Rorbach, Lindsey Van Haute, Aaron R D’Souza, Pedro Rebelo-Guiomar, Christopher A Powell, Ian Brierley, Andrew E Firth, Michal Minczuk
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-07-01
Series:eLife
Subjects:
mitochondria
mitochondrial RNA
mitoribosome
polyadenylation
mtPAP
ribosome profiling
Online Access:https://elifesciences.org/articles/27596

Internet

https://elifesciences.org/articles/27596

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