A Simple Approach to Bioconjugation at Diverse Levels: Metal-Free Click Reactions of Activated Alkynes with Native Groups of Biotargets without Prefunctionalization

The efficient bioconjugation of functional groups/molecules to targeted matrix and bio-related species drives the great development of material science and biomedicine, while the dilemma of metal catalysis, uneasy premodification, and limited reaction efficiency in traditional bioconjugation has res...

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Bibliographic Details
Main Authors: Xianglong Hu, Xueqian Zhao, Benzhao He, Zheng Zhao, Zheng Zheng, Pengfei Zhang, Xiujuan Shi, Ryan T. K. Kwok, Jacky W. Y. Lam, Anjun Qin, Ben Zhong Tang
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2018-01-01
Series:Research
Online Access:http://dx.doi.org/10.1155/2018/3152870