Anlotinib enhances the antitumor immunity of radiotherapy by activating cGAS/STING in non-small cell lung cancer

Abstract Radiation resistance and unsatisfactory efficacy of radioimmunotherapy are important barriers to non-small cell lung cancer (NSCLC) treatment. The impacts of anlotinib on radiation and tumor immune microenvironment (TIME) in NSCLC remain to be resolved. Here, we find anlotinib enhances radi...

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Bibliographic Details
Main Authors: Dong Han, Jiajia Zhang, Yawei Bao, Lei Liu, Ping Wang, Dong Qian
Format: Article
Language:English
Published: Nature Publishing Group 2022-11-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01256-2