miR-4716–3p and the target AKT2 Gene/rs2304186 SNP are associated with blood cancer pathogenesis in Pakistani population

miR-4716–3p and the target AKT2 Gene/rs2304186 SNP are associated with blood cancer pathogenesis in Pakistani population

AKT2 is crucial for cancer cells' invasion, metastasis, and survival. It is a possible downstream gene target of cancer glycolysis-related microRNAs. The study investigated the role of miRNA-4716–3p, rs2304186, and the AKT2 gene in blood cancer pathogenesis. RT-qPCR was used to analyze AKT2 gen...

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Bibliographic Details
Main Authors: Jairus Olumasai Nandwa, Azhar Mehmood, Ishrat Mahjabeen, Kayode Yomi Raheem, Mamoudou Hamadou, Mouhamed Z.K.A. Raimi, Mahmood A. Kayani
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-09-01
Series:Non-coding RNA Research
Subjects:
AKT2
Blood cancer
Polymorphism
miRNA-4716–3p
Biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054024000556

Internet

http://www.sciencedirect.com/science/article/pii/S2468054024000556

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