Essential Oil Derived From Eupatorium adenophorum Spreng. Mediates Anticancer Effect by Inhibiting STAT3 and AKT Activation to Induce Apoptosis in Hepatocellular Carcinoma

Essential Oil Derived From Eupatorium adenophorum Spreng. Mediates Anticancer Effect by Inhibiting STAT3 and AKT Activation to Induce Apoptosis in Hepatocellular Carcinoma

Eupatorium adenophorum Spreng. (EA) is a well-known noxious invasive species. Gas chromatography-mass spectrometry (GC-MS) analysis revealed that the essential oil derived from EA (EAEO) is mainly composed of sesquiterpenes. However, the pharmacological value of EAEO in hepatocellular carcinoma (HCC...

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Bibliographic Details
Main Authors: Hao Chen, Bei Zhou, Jie Yang, Xinhua Ma, Shihao Deng, Yun Huang, Yanzhang Wen, Jingquan Yuan, Xinzhou Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
Eupatorium adenophorum
essential oil
anticancer
hepatocellular carcinoma
apoptosis
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00483/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00483/full

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