Salt gradient and ion-pair mediated anion exchange of intact messenger ribonucleic acids

Small molecule drugs and protein-based therapeutics are widely used to treat various diseases, yet even more aspects of human health can be addressed through new modalities, like messenger RNA (mRNA). The complex nature and chemical structure of an mRNA molecule will require the development of new a...

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Bibliographic Details
Main Authors: Szabolcs Fekete, Hua Yang, Kevin Wyndham, Matthew Lauber
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Journal of Chromatography Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772391722000020