Modulation of Amyloidogenic Peptide Aggregation by Photoactivatable CO-Releasing Ruthenium(II) Complexes

Modulation of Amyloidogenic Peptide Aggregation by Photoactivatable CO-Releasing Ruthenium(II) Complexes

Three Ru(II)-based CO-releasing molecules featuring bidentate benzimidazole and terpyridine derivatives as ligands were investigated for their ability to modulate the aggregation process of the second helix of the C-terminal domain of nucleophosmin 1, namely nucleophosmin 1 (NPM1)<sub>264–277&...

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Bibliographic Details
Main Authors: Daniele Florio, Maria Cuomo, Ilaria Iacobucci, Giarita Ferraro, Ahmed M. Mansour, Maria Monti, Antonello Merlino, Daniela Marasco
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceuticals
Subjects:
modulators of amyloid peptide aggregation
metallodrugs
ruthenium(II) compounds
CO releasing molecules
Online Access:https://www.mdpi.com/1424-8247/13/8/171

Internet

https://www.mdpi.com/1424-8247/13/8/171

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