Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/β-Catenin Pathways via miR-130a

Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/β-Catenin Pathways via miR-130a

Curcumin exhibits anti-tumor effects in several cancers, including colorectal carcinoma (CRC), but the detailed mechanisms are still unclear. Here we studied the mechanisms underlying the anti-tumor effect of curcumin in colon cancer cells. SW480 cells were injected into mice to establish the xenogr...

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Bibliographic Details
Main Authors: Huiqiang Dou, Renhui Shen, Jianxin Tao, Longchang Huang, Haoze Shi, Hang Chen, Yixin Wang, Tong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Pharmacology
Subjects:
colon cancer
curcumin
Wnt signaling
anti-tumor
miRNA
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00877/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00877/full

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