The prognostic impact of TGF-β1, fascin, NF-κB and PKC-ζ expression in soft tissue sarcomas.

The prognostic impact of TGF-β1, fascin, NF-κB and PKC-ζ expression in soft tissue sarcomas.

AIMS: Transforming growth factor-β (TGF-β), fascin, nuclear factor-kappa B (NF-κB) p105, protein-kinase C-zeta (PKC-ζ), partioning-defective protein-6 (Par-6), E-cadherin and vimentin are tumor promoting molecules through mechanisms involved in cell dedifferentiation. In soft tissue sarcomas, their...

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Bibliographic Details
Main Authors: Andrej Valkov, Sveinung W Sorbye, Thomas K Kilvaer, Tom Donnem, Eivind Smeland, Roy M Bremnes, Lill-Tove Busund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3048407?pdf=render

Internet

http://europepmc.org/articles/PMC3048407?pdf=render

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