Nucleosomal DNA unwinding pathway through canonical and non-canonical histone disassembly

Nucleosomal DNA unwinding pathway through canonical and non-canonical histone disassembly

Abstract The nucleosome including H2A.B, a mammalian-specific H2A variant, plays pivotal roles in spermatogenesis, embryogenesis, and oncogenesis, indicating unique involvement in transcriptional regulation distinct from canonical H2A nucleosomes. Despite its significance, the exact regulatory mecha...

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Bibliographic Details
Main Authors: Hikaru Nozawa, Fritz Nagae, Satoshi Ogihara, Rina Hirano, Hirohito Yamazaki, Ryo Iizuka, Munetaka Akatsu, Tomoya Kujirai, Shoji Takada, Hitoshi Kurumizaka, Sotaro Uemura
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06856-5

Internet

https://doi.org/10.1038/s42003-024-06856-5

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