Stoichiometry of HLA class II-invariant chain oligomers.

BACKGROUND: The HLA gene complex encodes three class II isotypes, DR, DQ, and DP. HLA class II molecules are peptide receptors that present antigens for recognition by T lymphocytes. In antigen presenting cells, the assembly of matched α and β subunits to heterodimers is chaperoned by invariant chai...

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Bibliographic Details
Main Authors: Norbert Koch, Martin Zacharias, Angelika König, Sebastian Temme, Jürgen Neumann, Sebastian Springer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3043101?pdf=render