Stoichiometry of HLA class II-invariant chain oligomers.
BACKGROUND: The HLA gene complex encodes three class II isotypes, DR, DQ, and DP. HLA class II molecules are peptide receptors that present antigens for recognition by T lymphocytes. In antigen presenting cells, the assembly of matched α and β subunits to heterodimers is chaperoned by invariant chai...
Main Authors: | Norbert Koch, Martin Zacharias, Angelika König, Sebastian Temme, Jürgen Neumann, Sebastian Springer |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3043101?pdf=render |
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