Altered Treg Infiltration after Discoidin Domain Receptor 1 (DDR1) Inhibition and Knockout Promotes Tumor Growth in Lung Adenocarcinoma

Altered Treg Infiltration after Discoidin Domain Receptor 1 (DDR1) Inhibition and Knockout Promotes Tumor Growth in Lung Adenocarcinoma

Lung cancer is the leading cause of cancer-related death worldwide. Discoidin domain receptor 1 (DDR1), a tyrosine kinase receptor, has been associated with poor prognosis in patients with non-small cell lung cancer (NSCLC). However, its role in tumorigenesis remains poorly understood. This work aim...

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Bibliographic Details
Main Authors: Kathrin Maitz, Paulina Valadez-Cosmes, Sofia Raftopoulou, Oliver Kindler, Melanie Kienzl, Hamid Bolouri, A. McGarry Houghton, Rudolf Schicho, Akos Heinemann, Julia Kargl
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cancers
Subjects:
non-small cell lung cancer
discoidin domain receptor 1
tumor microenvironment
regulatory T cells
Online Access:https://www.mdpi.com/2072-6694/15/24/5767

Internet

https://www.mdpi.com/2072-6694/15/24/5767

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