Single-cell multiome sequencing clarifies enteric glial diversity and identifies an intraganglionic population poised for neurogenesis

Summary: The enteric nervous system (ENS) consists of glial cells (EGCs) and neurons derived from neural crest precursors. EGCs retain capacity for large-scale neurogenesis in culture, and in vivo lineage tracing has identified neurons derived from glial cells in response to inflammation. We thus hy...

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Bibliographic Details
Main Authors: Richard A. Guyer, Rhian Stavely, Keiramarie Robertson, Sukhada Bhave, Jessica L. Mueller, Nicole M. Picard, Ryo Hotta, Julia A. Kaltschmidt, Allan M. Goldstein
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472300205X