Globally Defining the Effects of Amino Acid Mutations across a Picornavirus Capsid

RNA<b> </b>viruses are characterized by their extreme mutation rates, which play key roles in their biology and give them the ability to rapidly adapt to new environments. However, non-synonymous mutations tend to be largely deleterious to protein function, raising the question of how th...

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Bibliographic Details
Main Authors: Florian Mattenberger, Ron Geller
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Proceedings
Subjects:
Online Access:https://www.mdpi.com/2504-3900/50/1/111