Characterization of neuronal spiking patterns in the medial prefrontal cortex under varied general anesthetics in mice

Characterization of neuronal spiking patterns in the medial prefrontal cortex under varied general anesthetics in mice

Abstract Purpose The mechanisms underlying reversible unconsciousness induced by general anesthetics remain unclear. This study aimed to investigate the effects of four commonly used anesthetics on neuronal spiking patterns in layer 5 of the medial prefrontal cortex (mPFC). Methods In vivo multi-cha...

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Bibliographic Details
Main Authors: Xiangyu Hu, Jingyao Jiang, Yu Leng, Yaoxin Yang, Donghang Zhang, Ke Li, Tao Zhu, Peng Liang, Cheng Zhou
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Anesthesiology and Perioperative Science
Subjects:
mPFC
General anesthetics
Neuronal spiking
Loss of righting reflex
Animal model
Online Access:https://doi.org/10.1007/s44254-025-00092-8

Internet

https://doi.org/10.1007/s44254-025-00092-8

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