The role of IDH1/2 mutations in the pathogenesis of secondary glioblastomas

ABSTRACT Diffuse astrocytoma and glioblastoma (GBM) constitute a group of diffusely infiltrating astrocytic neoplasms, which more commonly arise in cerebral hemispheres of adults. The prevalence of malignant transformation of diffuse astrocytoma to anaplastic astrocytoma and GBM varies from 40% to 7...

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Bibliographic Details
Main Author: Eduardo Cambruzzi
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2017-10-01
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442017000500338&tlng=en