An Overview of NRF2-Activating Compounds Bearing α,β-Unsaturated Moiety and Their Antioxidant Effects

An Overview of NRF2-Activating Compounds Bearing α,β-Unsaturated Moiety and Their Antioxidant Effects

The surge of scientific interest in the discovery of Nuclear Factor Erythroid 2 (NFE2)-Related Factor 2 (NRF2)-activating molecules underscores the importance of NRF2 as a therapeutic target especially for oxidative stress. The chemical reactivity and biological activities of several bioactive compo...

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Bibliographic Details
Main Authors: Melford Chuka Egbujor, Brigitta Buttari, Elisabetta Profumo, Pelin Telkoparan-Akillilar, Luciano Saso
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
NRF2
KEAP1
α,β-unsaturated moiety
carbonyl
sulfonyl
sulfinyl
Online Access:https://www.mdpi.com/1422-0067/23/15/8466

Internet

https://www.mdpi.com/1422-0067/23/15/8466

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