Stretch of the papillary insertion triggers reentrant arrhythmia: an in silico patient study

Stretch of the papillary insertion triggers reentrant arrhythmia: an in silico patient study

BackgroundThe electrophysiological mechanism connecting mitral valve prolapse (MVP), premature ventricular complexes and life-threatening ventricular arrhythmia is unknown. A common hypothesis is that stretch activated channels (SACs) play a significant role. SACs can trigger depolarizations or shor...

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Bibliographic Details
Main Authors: Lena Myklebust, Giulia Monopoli, Gabriel Balaban, Eivind Westrum Aabel, Margareth Ribe, Anna Isotta Castrini, Nina Eide Hasselberg, Cecilie Bugge, Christian Five, Kristina Haugaa, Mary M. Maleckar, Hermenegild Arevalo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Physiology
Subjects:
mitral annulus disjunction
mitral valve prolapse
ventricular reentry
stretch activated channels
computational modeling
cardiac electrophysiology
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2024.1447938/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2024.1447938/full

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