UV-Inactivated rVSV-M2e-Based Influenza Vaccine Protected against the H1N1 Influenza Challenge

UV-Inactivated rVSV-M2e-Based Influenza Vaccine Protected against the H1N1 Influenza Challenge

Background: To investigate the immune responses and protection ability of ultraviolet light (UV)-inactivated recombinant vesicular stomatitis (rVSV)-based vectors that expressed a fusion protein consisting of four copies of the influenza matrix 2 protein ectodomain (tM2e) and the Dendritic Cell (DC)...

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Bibliographic Details
Main Authors: Titus Abiola Olukitibi, Zhujun Ao, Hiva Azizi, Maggie J Ouyang, Tosin Omole, Lyle McKinnon, Darwyn Kobasa, Kevin Coombs, Gary Kobinger, Xiaojian Yao
Format: Article
Language:English
Published: IMR Press 2024-05-01
Series:Frontiers in Bioscience-Landmark
Subjects:
uv-inactivation
influenza
recombinant vesicular stomatitis virus
ebola glycoprotein
m2 ectodomain
antibody-dependent cellular cytotoxicity (adcc)
Online Access:https://www.imrpress.com/journal/FBL/29/5/10.31083/j.fbl2905195

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https://www.imrpress.com/journal/FBL/29/5/10.31083/j.fbl2905195

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