A validated LC–MS/MS method for analysis of Cabergoline in human plasma with its implementation in a bioequivalent study: investigation of method greenness

A validated LC–MS/MS method for analysis of Cabergoline in human plasma with its implementation in a bioequivalent study: investigation of method greenness

Abstract Cabergoline (CAB) is effective prolactin lowering drug. Evaluation of the bioequivalence for the new test product (0.5 mg CAB film-coated tablets) in Egypt is strongly needed for approval of the drug by the official health authority. Therefore, a highly sensitive and rapid (LC–MS/MS) method...

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Bibliographic Details
Main Authors: Khaled Shalaby, Saleh Alghamdi, Mohammed Gamal, Lobna Mohammed Abd Elhalim, Rehab Moussa Tony
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Chemistry
Subjects:
LC–MS/MS
Bioequivalence
Pharmacokinetic
Cabergoline
Dostinex
Bioanalytical method validation
Online Access:https://doi.org/10.1186/s13065-022-00862-6

Internet

https://doi.org/10.1186/s13065-022-00862-6

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