Biomimetic Redox-Responsive Mesoporous Organosilica Nanoparticles Enhance Cisplatin-Based Chemotherapy

Biomimetic Redox-Responsive Mesoporous Organosilica Nanoparticles Enhance Cisplatin-Based Chemotherapy

Cisplatin-based chemotherapy is dominated in several cancers; however, insufficient therapeutic outcomes and systemic toxicity hamper their clinical applications. Controlled release of cisplatin and reducing inactivation remains an urgent challenge to overcome. Herein, diselenide-bridged mesoporous...

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Bibliographic Details
Main Authors: Fangman Chen, Fan Zhang, Yanbin Wang, Jiahui Peng, Lei Cao, Qian Mei, Mingfeng Ge, Li Li, Meiwan Chen, Wen-fei Dong, Zhimin Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
cisplatin
mesoporous silica nanoparticles
glutathione depletion
biomimetic nanocarrier
degradation
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.860949/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.860949/full

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