Injectable phase-separated tetra-armed poly(ethylene glycol) hydrogel scaffold allows sustained release of growth factors to enhance the repair of critical bone defects

Injectable phase-separated tetra-armed poly(ethylene glycol) hydrogel scaffold allows sustained release of growth factors to enhance the repair of critical bone defects

With the rising prevalence of bone-related injuries, it is crucial to improve treatments for fractures and defects. Tissue engineering offers a promising solution in the form of injectable hydrogel scaffolds that can sustain the release of growth factors like bone morphogenetic protein-2 (BMP-2) for...

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Bibliographic Details
Main Authors: Shant Nepal, Jinyan Si, Shohei Ishikawa, Masaki Nishikawa, Yasuyuki Sakai, Aya M. Akimoto, Hiroyuki Okada, Shinsuke Ohba, Ung-il Chung, Takamasa Sakai, Hironori Hojo
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Regenerative Therapy
Subjects:
Polyethylene glycol
Injectable hydrogel
Gel-gel phase separation
Growth factors
Sustained release
Bone regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S235232042300113X

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http://www.sciencedirect.com/science/article/pii/S235232042300113X

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