Walk on the wild side: SIV infection in African non-human primate hosts—from the field to the laboratory

Walk on the wild side: SIV infection in African non-human primate hosts—from the field to the laboratory

HIV emerged following cross-species transmissions of simian immunodeficiency viruses (SIVs) that naturally infect non-human primates (NHPs) from Africa. While HIV replication and CD4+ T-cell depletion lead to increased gut permeability, microbial translocation, chronic immune activation, and systemi...

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Bibliographic Details
Main Authors: Anna J. Jasinska, Cristian Apetrei, Ivona Pandrea
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
AIDS - acquired immunodeficiency syndrome
HIV - human immunodeficiency virus
nonhuman primate (NHP)
African green monkey (AGM) (Chlorocebus aethiops)
mucosal immune barrier
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1060985/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1060985/full

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