Increased apolipoprotein E and decreased TNF‐α in the cerebrospinal fluid of nondemented APOE‐ε4 carriers

Increased apolipoprotein E and decreased TNF‐α in the cerebrospinal fluid of nondemented APOE‐ε4 carriers

Abstract Aim The ε4 allele of apolipoprotein E gene (APOE) is a well‐known risk factor of late‐onset Alzheimer's disease. However, little is known why this variant confers a risk for Alzheimer's disease. The aim of this study was to examine the influence of the APOE genotype on cerebrospin...

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Bibliographic Details
Main Authors: Daimei Sasayama, Kotaro Hattori, Yuuki Yokota, Ryo Matsumura, Toshiya Teraishi, Sumiko Yoshida, Hiroshi Kunugi
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Neuropsychopharmacology Reports
Subjects:
alzheimer disease
apolipoproteins E
biomarkers
cerebrospinal fluid proteins
tumor necrosis factor‐alpha
Online Access:https://doi.org/10.1002/npr2.12110

Internet

https://doi.org/10.1002/npr2.12110

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