The BDNF Val66Met polymorphism has opposite effects on memory circuits of multiple sclerosis patients and controls.

Episodic memory deficits are frequent symptoms in Multiple Sclerosis and have been associated with dysfunctions of the hippocampus, a key region for learning. However, it is unclear whether genetic factors that influence neural plasticity modulate episodic memory in MS. We thus studied how the Brain...

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Bibliographic Details
Main Authors: Francesco Fera, Luca Passamonti, Antonio Cerasa, Maria Cecilia Gioia, Maria Liguori, Ida Manna, Paola Valentino, Aldo Quattrone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3623818?pdf=render