Understanding Mechanisms Underlying Non-Alcoholic Fatty Liver Disease (NAFLD) in Mental Illness: Risperidone and Olanzapine Alter the Hepatic Proteomic Signature in Mice

Understanding Mechanisms Underlying Non-Alcoholic Fatty Liver Disease (NAFLD) in Mental Illness: Risperidone and Olanzapine Alter the Hepatic Proteomic Signature in Mice

Patients with severe mental illness have increased mortality, often linked to cardio-metabolic disease. Non-alcoholic fatty liver disease (NAFLD) incidence is higher in patients with schizophrenia and is exacerbated with antipsychotic treatment. NAFLD is associated with obesity and insulin resistanc...

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Bibliographic Details
Main Authors: Bahman Rostama, Megan Beauchemin, Celeste Bouchard, Elizabeth Bernier, Calvin P. H. Vary, Meghan May, Karen L. Houseknecht
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
antipsychotic
liver
proteome
energy metabolism
nonalcoholic fatty liver disease
steatosis
Online Access:https://www.mdpi.com/1422-0067/21/24/9362

Internet

https://www.mdpi.com/1422-0067/21/24/9362

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