Case report: Common clonal origin of concurrent langerhans cell histiocytosis and acute myeloid leukemia

Case report: Common clonal origin of concurrent langerhans cell histiocytosis and acute myeloid leukemia

Langerhans cell histiocytosis (LCH) and acute myeloid leukemia (AML) are distinct entities of blood neoplasms, and the exact developmental origin of both neoplasms are considered be heterogenous among patients. However, reports of concurrent LCH and AML are rare. Herein we report a novel case of con...

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Bibliographic Details
Main Authors: Shintaro Kazama, Kazuaki Yokoyama, Toshimitsu Ueki, Hiroko Kazumoto, Hidetoshi Satomi, Masahiko Sumi, Ichiro Ito, Nozomi Yusa, Rika Kasajima, Eigo Shimizu, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Yukihisa Tanaka, Tamami Denda, Yasunori Ota, Arinobu Tojo, Hikaru Kobayashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
langerhans cell histiocytosis
acute myeloid leukemia
NRAS
MAPK pathway
histiocytic disorders
dendritic cells
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.974307/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.974307/full

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