Rational engineering of lung alveolar epithelium

Abstract Engineered whole lungs may one day expand therapeutic options for patients with end-stage lung disease. However, the feasibility of ex vivo lung regeneration remains limited by the inability to recapitulate mature, functional alveolar epithelium. Here, we modulate multimodal components of t...

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Bibliographic Details
Main Authors: Katherine L. Leiby, Yifan Yuan, Ronald Ng, Micha Sam Brickman Raredon, Taylor S. Adams, Pavlina Baevova, Allison M. Greaney, Karen K. Hirschi, Stuart G. Campbell, Naftali Kaminski, Erica L. Herzog, Laura E. Niklason
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-023-00295-2