Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learning

Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learning

Abstract Background Blood circulating microRNAs that are specific for Alzheimer’s disease (AD) can be identified from differentially expressed microRNAs (DEmiRNAs). However, non-reproducible and inconsistent reports of DEmiRNAs hinder biomarker development. The most reliable DEmiRNAs can be identifi...

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Bibliographic Details
Main Authors: Sze Chung Yuen, Xiaonan Liang, Hongmei Zhu, Yongliang Jia, Siu-wai Leung
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Meta-analysis
MicroRNAs
ABMDA
Biomarkers
Neuroinflammation
Online Access:https://doi.org/10.1186/s13195-021-00862-z

Internet

https://doi.org/10.1186/s13195-021-00862-z

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