A novel regulator of selective autophagy: TNIP1/ABIN-1 modulates mitophagy

TNIP1/ABIN-1 is a novel inhibitor of inflammation and cell death. In our study, we elucidated the MAP1LC3/LC3 (microtubule associated protein 1 light chain 3)-interacting region (LIR) 1 and 2 motifs of TNIP1-dependent direct binding to LC3B-II and subsequent colocalization on phagophores. In additio...

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Bibliographic Details
Main Authors: Rosetta Merline, Liliana Schaefer
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Autophagy Reports
Subjects:
Online Access:http://dx.doi.org/10.1080/27694127.2023.2165269