Effect of Alpha-1 Antitrypsin on CFTR Levels in Primary Human Airway Epithelial Cells Grown at the Air-Liquid-Interface

Effect of Alpha-1 Antitrypsin on CFTR Levels in Primary Human Airway Epithelial Cells Grown at the Air-Liquid-Interface

The cystic fibrosis transmembrane conductance regulator (CFTR) gene is influenced by the fundamental cellular processes like epithelial differentiation/polarization, regeneration and epithelial–mesenchymal transition. Defects in CFTR protein levels and/or function lead to decreased airway surface li...

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Bibliographic Details
Main Authors: Frauke Stanke, Sabina Janciauskiene, Stephanie Tamm, Sabine Wrenger, Ellen Luise Raddatz, Danny Jonigk, Peter Braubach
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
alpha1-antitrypsin
CFTR
epithelial cells
cystic fibrosis
air-liquid-interface culture
Online Access:https://www.mdpi.com/1420-3049/26/9/2639

Internet

https://www.mdpi.com/1420-3049/26/9/2639

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