Inhibition of DNA Repair Mechanisms and Induction of Apoptosis in Triple Negative Breast Cancer Cells Expressing the Human Herpesvirus 6 U94

Inhibition of DNA Repair Mechanisms and Induction of Apoptosis in Triple Negative Breast Cancer Cells Expressing the Human Herpesvirus 6 U94

Triple-negative breast cancer (TNBC) accounts for 15−20% of all breast cancers. In spite of initial good response to chemotherapy, the prognosis of TNBC remains poor and no effective specific targeted therapy is readily available. Recently, we demonstrated the ability of U94, the latency g...

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Bibliographic Details
Main Authors: Francesca Caccuri, Michele Sommariva, Stefania Marsico, Francesca Giordano, Alberto Zani, Arianna Giacomini, Cornel Fraefel, Andrea Balsari, Arnaldo Caruso
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
HHV-6 U94
HSV-1 amplicon vector
triple negative breast cancer cells
gene expression profile
DNA repair
cell cycle
apoptosis
Online Access:https://www.mdpi.com/2072-6694/11/7/1006

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https://www.mdpi.com/2072-6694/11/7/1006

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