SARS-CoV-2 main protease inhibitors from the stem barks of Discoglypremna caloneura (Pax) Prain (Euphorbiaceae) and Pterocarpus erinaceus Poir (Fabaceae) and their molecular docking investigation

SARS-CoV-2 main protease inhibitors from the stem barks of Discoglypremna caloneura (Pax) Prain (Euphorbiaceae) and Pterocarpus erinaceus Poir (Fabaceae) and their molecular docking investigation

Abstract The main viral protease (Mpro) of SARS-CoV-2 provides an excellent target for antivirals, due to its essential and conserved function in the viral replication cycle. We reported in this study, the SARS-CoV-2 main protease inhibitory effect of twelve compounds isolated from D. caloneura and...

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Bibliographic Details
Main Authors: Paul Toukam Djouonzo, Md Sofequl Islam Mukim, Pamela Nangmo Kemda, Theodora Kopa Kowa, Alembert Tiabou Tchinda, Gabriel Agbor Agbor, Cheol-Ho Pan, Dae-Geun Song
Format: Article
Language:English
Published: SpringerOpen 2023-11-01
Series:Applied Biological Chemistry
Subjects:
Baicalein
Derivatives
Friedelin
Molecular docking
Mpro inhibitory effect
Online Access:https://doi.org/10.1186/s13765-023-00833-y

Internet

https://doi.org/10.1186/s13765-023-00833-y

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