Structural and Functional Analysis of the Pyridoxal Phosphate Homeostasis Protein YggS from <i>Fusobacterium nucleatum</i>

Structural and Functional Analysis of the Pyridoxal Phosphate Homeostasis Protein YggS from <i>Fusobacterium nucleatum</i>

Pyridoxal 5′-phosphate (PLP) is the active form of vitamin B6, but it is highly reactive and poisonous in its free form. YggS is a PLP-binding protein found in bacteria and humans that mediates PLP homeostasis by delivering PLP to target enzymes or by performing a protective function. Several bioche...

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Bibliographic Details
Main Authors: Shanru He, Yuanyuan Chen, Lulu Wang, Xue Bai, Tingting Bu, Jie Zhang, Ming Lu, Nam-Chul Ha, Chunshan Quan, Ki Hyun Nam, Yongbin Xu
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
pyridoxal 5′-phosphate
PLP
YggS
<i>Fusobacterium nucleatum</i>
crystal structure
Online Access:https://www.mdpi.com/1420-3049/27/15/4781

Internet

https://www.mdpi.com/1420-3049/27/15/4781

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