Glucose Transporter-2 Regulation of Male versus Female Hypothalamic Astrocyte MAPK Expression and Activation: Impact of Glucose

Glucose Transporter-2 Regulation of Male versus Female Hypothalamic Astrocyte MAPK Expression and Activation: Impact of Glucose

The plasma membrane glucose transporter (GLUT)-2 is unique among GLUT family proteins in that it also functions as a glucose sensor. GLUT2 imposes sex-dimorphic control of hypothalamic astrocyte glucose storage and catabolism by unknown mechanisms. Mitogen-activated protein kinase (MAPK) signaling c...

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Bibliographic Details
Main Authors: Madhu Babu Pasula, Sagor C. Roy, Khaggeswar Bheemanapally, Paul W. Sylvester, Karen P. Briski
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Neuroglia
Subjects:
GLUT2
p38 MAPK
ERK1/2
SAPK/JNK
sex differences
primary astrocyte cultures
Online Access:https://www.mdpi.com/2571-6980/4/3/11

Internet

https://www.mdpi.com/2571-6980/4/3/11

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