5-Bromo-2’-deoxyuridine labeling: historical perspectives, factors influencing the detection, toxicity, and its implications in the neurogenesis

5-Bromo-2’-deoxyuridine labeling: historical perspectives, factors influencing the detection, toxicity, and its implications in the neurogenesis

The halopyrimidine 5-bromo-2′-deoxyuridine (BrdU) is an exogenous marker of DNA synthesis. Since the introduction of monoclonal antibodies against BrdU, an increasing number of methodologies have been used for the immunodetection of this synthesized bromine-tagged base analogue into replicating DNA....

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Bibliographic Details
Main Author: Joaquín Martí-Clúa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Neural Regeneration Research
Subjects:
5-bromo-2′-deoxyuridine; adult neurogenesis; human adult neurogenesis; labeling; pitfalls; prenatal neurogenesis; proliferation; s-phase; suturing s-phase; toxicity
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=2;spage=302;epage=308;aulast=Martí-Clúa

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=2;spage=302;epage=308;aulast=Martí-Clúa

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