Protection and Repair of the Nigrostriatal Pathway with Stem-Cell-Derived Carotid Body Glomus Cell Transplants in Chronic MPTP Parkinsonian Model

Protection and Repair of the Nigrostriatal Pathway with Stem-Cell-Derived Carotid Body Glomus Cell Transplants in Chronic MPTP Parkinsonian Model

Antiparkinsonian carotid body (CB) cell therapy has been proven to be effective in rodent and nonhuman primate models of Parkinson’s disease (PD), exerting trophic protection and restoration of the dopaminergic nigrostriatal pathway. These neurotrophic actions are mediated through the release of hig...

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Bibliographic Details
Main Authors: Javier Villadiego, Ana B. Muñoz-Manchado, Verónica Sobrino, Victoria Bonilla-Henao, Nela Suárez-Luna, Patricia Ortega-Sáenz, Ricardo Pardal, José López-Barneo, Juan J. Toledo-Aral
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
cell therapy
carotid body stem cells
neuroprotection
neurorestoration
Online Access:https://www.mdpi.com/1422-0067/24/6/5575

Internet

https://www.mdpi.com/1422-0067/24/6/5575

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