Antidiabetic efficacy of lactoferrin in type 2 diabetic pediatrics; controlling impact on PPAR-γ, SIRT-1, and TLR4 downstream signaling pathway

Antidiabetic efficacy of lactoferrin in type 2 diabetic pediatrics; controlling impact on PPAR-γ, SIRT-1, and TLR4 downstream signaling pathway

Abstract The current study aims to investigate the antidiabetic efficacy of camel milk-derived lactoferrin and potential involvement of PPAR-γ and SIRT-1 via TLR-4/NFκB signaling pathway in obese diabetic pediatric population. Sixty young obese patients with type 2 diabetes were selected from the Pe...

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Bibliographic Details
Main Authors: Waleed A. Mohamed, Mona F. Schaalan
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Lactoferrin
T2DM
PPAR-γ
SIRT-1
NFκB
Online Access:http://link.springer.com/article/10.1186/s13098-018-0390-x

Internet

http://link.springer.com/article/10.1186/s13098-018-0390-x

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