Dynamic transcription factor networks in epithelial-mesenchymal transition in breast cancer models.

The epithelial-mesenchymal transition (EMT) is a complex change in cell differentiation that allows breast carcinoma cells to acquire invasive properties. EMT involves a cascade of regulatory changes that destabilize the epithelial phenotype and allow mesenchymal features to manifest. As transcripti...

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Bibliographic Details
Main Authors: Anaar Siletz, Michael Schnabel, Ekaterina Kniazeva, Andrew J Schumacher, Seungjin Shin, Jacqueline S Jeruss, Lonnie D Shea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620167?pdf=render