Discovery of a sugar-based nanoparticle universally existing in boiling herbal water extracts and their immunostimulant effect

Herbal medicine is mainly prepared from boiling herbal water extracts. Many epoch-making immunosuppressant drugs, such as glycyrrhizic acid (old example) and FTY720 (current example), were developed from herbal secondary metabolites in the boiling water extract by partition with organic solvents. Ho...

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Bibliographic Details
Main Authors: Hirofumi Iitsuka, Keiichi Koizumi, Akiko Inujima, Mikiko Suzaki, Yusuke Mizuno, Yoshiki Takeshita, Takeshi Eto, Yoshiki Otsuka, Ryo Shimada, Mengxin Liu, Keisuke Ikeda, Minoru Nakano, Ryo Suzuki, Kazuo Maruyama, Yue Zhou, Hiroaki Sakurai, Naotoshi Shibahara
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580818301766