Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis

Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis

Insulin-like growth factor (IGF) signaling controls the development and growth of many organs, including the lung. Loss of function of <i>Igf1</i> or its receptor <i>Igf1r</i> impairs lung development and leads to neonatal respiratory distress in mice. Although many component...

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Bibliographic Details
Main Authors: Vahid Kheirollahi, Ali Khadim, Georgios Kiliaris, Martina Korfei, Margarida Maria Barroso, Ioannis Alexopoulos, Ana Ivonne Vazquez-Armendariz, Malgorzata Wygrecka, Clemens Ruppert, Andreas Guenther, Werner Seeger, Susanne Herold, Elie El Agha
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
IGF1
IGF1R
lung development
bleomycin-induced pulmonary fibrosis
idiopathic pulmonary fibrosis
Online Access:https://www.mdpi.com/2073-4409/11/12/1973

Internet

https://www.mdpi.com/2073-4409/11/12/1973

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