MiRNA-424-5p Suppresses Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma and Attenuates Expression of O-GlcNAc-Transferase

MiRNA-424-5p Suppresses Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma and Attenuates Expression of O-GlcNAc-Transferase

MicroRNAs (miRNAs) are non-coding post-transcriptional regulators of gene expression that are dysregulated in clear cell renal cell carcinoma (ccRCC) and play an important role in tumor progression. Our prior work identified a subset of miRNAs in pT1 ccRCC tumors, including miR-424-5p, that are asso...

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Bibliographic Details
Main Authors: Thomas J. Kalantzakos, Travis B. Sullivan, Thales Gloria, David Canes, Alireza Moinzadeh, Kimberly M. Rieger-Christ
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
biomarkers
clear cell renal cell cancer (ccRCC)
microRNA
O-GlcNAc-transferase (OGT)
proliferation
migration
Online Access:https://www.mdpi.com/2072-6694/13/20/5160

Internet

https://www.mdpi.com/2072-6694/13/20/5160

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