Clinical Impact of Immune Checkpoint Inhibitor (ICI) Response, DNA Damage Repair (DDR) Gene Mutations and Immune-Cell Infiltration in Metastatic Melanoma Subtypes

Clinical Impact of Immune Checkpoint Inhibitor (ICI) Response, DNA Damage Repair (DDR) Gene Mutations and Immune-Cell Infiltration in Metastatic Melanoma Subtypes

Molecular and histopathological analysis of melanoma subtypes has revealed distinct epidemiological, genetic, and clinical features. However, immunotherapy for advanced metastatic melanoma patients does not differ based on subtype. Response to immune checkpoint inhibitors (ICI) has been shown to var...

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Bibliographic Details
Main Authors: Charlotte Andrieu, Niamh McNamee, Anne-Marie Larkin, Alanna Maguire, Roopika Menon, Judith Mueller-Eisert, Noel Horgan, Susan Kennedy, Giuseppe Gullo, John Crown, Naomi Walsh
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Medical Sciences
Subjects:
cutaneous melanoma
uveal melanoma
head and neck melanoma
mucosal melanoma
acral lentiginous melanoma
immunotherapy
Online Access:https://www.mdpi.com/2076-3271/10/2/26

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https://www.mdpi.com/2076-3271/10/2/26

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