The effect of high-dietary K+ (HK) on Kir4.1/Kir5.1 and ROMK in the distal convoluted tubule (DCT) is not affected by gender and Cl− content of the diet

The effect of high-dietary K+ (HK) on Kir4.1/Kir5.1 and ROMK in the distal convoluted tubule (DCT) is not affected by gender and Cl− content of the diet

Basolateral potassium channels in the distal convoluted tubule (DCT) are composed of inwardly-rectifying potassium channel 4.1 (Kir4.1) and Kir5.1. Kir4.1 interacts with Kir5.1 to form a 40 pS K+ channel which is the only type K+ channel expressed in the basolateral membrane of the DCT. Moreover, Ki...

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Bibliographic Details
Main Authors: Xin-Xin Meng, Hao Zhang, Gui-Lin Meng, Shao-Peng Jiang, Xin-Peng Duan, Wen-Hui Wang, Ming-Xiao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Physiology
Subjects:
renal K+ excretion
thiazide-sensitive
NCC
KCNJ1
KCNJ10
Kcnj16
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.1039029/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.1039029/full

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